ZAPA (sulfate) (Standard)
ZAPA (sulfate) (Standard) is the analytical standard of ZAPA (sulfate). This product is intended for research and analytical applications. ZAPA sulfate is an agonist at low affinity GABAA-receptors. ZAPA sulfate induces membrane hyperpolarization of the Ascaris muscle cell with an EC50 of 10.3 μM[1][2].
Product Specifications
CAS Number
371962-01-5
Target
GABA Receptor; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
O=C(O)/C=C\SC(N)=N.O=S(O)(O)=O
Molecular Formula
C4H8N2O6S2
Molecular Weight
244.25
References & Citations
[1]Yokogawa T, et al. Analysis of GABAA‐and GABAB‐receptor mediated effects on intracellular Ca2+ in DRG hybrid neurones. British journal of pharmacology, 2001, 134 (1) : 98-107.|[2]Holden-Dye L, et al. ZAPA, (Z) -3-[ (aminoiminomethyl) thio]-2-propenoic acid hydrochloride, a potent agonist at GABA-receptors on the Ascaris muscle cell. Br J Pharmacol. 1988 Sep;95 (1) :3-5.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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