ZAPA (sulfate) (Standard)

ZAPA (sulfate) (Standard) is the analytical standard of ZAPA (sulfate) (HY-100799) . This product is intended for research and analytical applications. ZAPA sulfate is an agonist at low affinity GABAA-receptors. ZAPA sulfate induces membrane hyperpolarization of the Ascaris muscle cell with an EC50 of 10.3 μM[1][2].

Product Specifications

CAS Number

[371962-01-5]

Target

GABA Receptor; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

O=C(O)/C=C\SC(N)=N.O=S(O)(O)=O

Molecular Formula

C4H8N2O6S2

Molecular Weight

244.25

References & Citations

[1]Yokogawa T, et al. Analysis of GABAA‐and GABAB‐receptor mediated effects on intracellular Ca2+ in DRG hybrid neurones. British journal of pharmacology, 2001, 134 (1) : 98-107.|[2]Holden-Dye L, et al. ZAPA, (Z) -3-[ (aminoiminomethyl) thio]-2-propenoic acid hydrochloride, a potent agonist at GABA-receptors on the Ascaris muscle cell. Br J Pharmacol. 1988 Sep;95 (1) :3-5.