URB602 (Standard)
URB602 (Standard) is the analytical standard of URB602. This product is intended for research and analytical applications. URB602 is a selective monoacylglycerol lipase (MGL) inhibitor, which inhibits rat brain MGL with IC50 of 28±4 μM through a noncompetitive mechanism.
Product Specifications
CAS Number
565460-15-3
UNSPSC
12352005
Target
Bacterial; Reference Standards
Related Pathways
Anti-infection; Others
Field of Research
Cancer
Smiles
O=C(OC1CCCCC1)NC2=CC(C3=CC=CC=C3)=CC=C2
Molecular Formula
C19H21NO2
Molecular Weight
295.38
References & Citations
[1]Hohmann AG, et al. An endocannabinoid mechanism for stress-induced analgesia. Nature. 2005 Jun 23;435 (7045) :1108-12.|[2]King AR, et al. URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices. Chem Biol. 2007 Dec;14 (12) :1357-65.|[3]Duncan M, et al. Distribution and function of monoacylglycerol lipase in the gastrointestinal tract. Am J Physiol Gastrointest Liver Physiol. 2008 Dec;295 (6) :G1255-65.|[4]Guindon J, et al. Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. Br J Pharmacol. 2011 Aug;163 (7) :1464-78.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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