DACA (Standard)

DACA (Standard) is the analytical standard of DACA (HY-100777) . This product is intended for research and analytical applications. DACA (XR 5000) is a blood-brain barrier-penetrating topoisomerase I and II inhibitor. DACA can be used in the research of colorectal cancer, leukemia and lung cancer[1][2][3][4].

Product Specifications

CAS Number

[89459-25-6]

UNSPSC

12352005

Target

Reference Standards; Topoisomerase

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Cancer

Smiles

O=C(C1=CC=CC2=CC3=CC=CC=C3N=C12)NCCN(C)C

Molecular Formula

C18H19N3O

Molecular Weight

293.36

References & Citations

[1]Padget K, et al. An investigation into the formation of N- [2- (dimethylamino) ethyl]acridine-4-carboxamide (DACA) and 6-[2- (dimethylamino) ethylamino]- 3-hydroxy-7H-indeno[2, 1-C]quinolin-7-one dihydrochloride (TAS-103) stabilised DNA topoisomerase I and II cleavable complexes in human leukaemia cells. Biochem Pharmacol. 2000;60 (6) :817-821.