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Fezagepras (sodium) (Standard)

Fezagepras (sodium) (Standard) is the analytical standard of Fezagepras (sodium) . This product is intended for research and analytical applications. Fezagepras (Setogepram) sodium acts as an orally active agonist for GPR40 and as an antagonist or inverse agonist for GPR84[1]. Fezagepras sodium decreases renal, liver and pancreatic fibrosis[1][2]. Fezagepras sodium exerts anti-fibrotic, anti-inflammatory and anti-proliferative actions[2].

Product Specifications

CAS Number

1254472-97-3

Product Name Alternative

Setogepram (sodium) (Standard) ; PBI-4050 (sodium) (Standard)

UNSPSC

12352005

Target

Free Fatty Acid Receptor; GPR84; Reference Standards

Related Pathways

GPCR/G Protein; Others

Field of Research

Metabolic Disease; Inflammation/Immunology

Smiles

O=C(O[Na])CC1=CC(CCCCC)=CC=C1

Molecular Formula

C13H17NaO2

Molecular Weight

228.26

References & Citations

[1]Li Y, et al. Fatty acid receptor modulator PBI-4050 inhibits kidney fibrosis and improves glycemic control. JCI Insight. 2018 May 17;3 (10) . pii: 120365.|[2]Grouix B, et al. PBI-4050 Reduces Stellate Cell Activation and Liver Fibrosis through Modulation of Intracellular ATP Levels and the Liver Kinase B1/AMP-Activated Protein Kinase/Mammalian Target of Rapamycin Pathway. J Pharmacol Exp Ther. 2018 Oct;367 (1) :71-81.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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