YUKA1 (Standard)
YUKA1 (Standard) is the analytical standard of YUKA1 (HY-100764) . This product is intended for research and analytical applications. YUKA1 is a potent and cell permeable Lysine demethylase 5A (KDM5A) inhibitor, with an IC50 of 2.66 μM. YUKA1 has less inhibitory active on KDM5C (IC50 = 7.12 μM) and is inactive on KDM5B, KDM6A or KDM6B. YUKA1 can increase H3K4me3 levels and inhibit cell proliferation. YUKA1 can be used for the research of cancer, such as lung and breast cancers[1].
Product Specifications
CAS Number
[708991-09-7]
Target
Histone Demethylase; Reference Standards
Related Pathways
Epigenetics; Others
Field of Research
Cancer
Smiles
C=CCOC1=C(CNN2C(NN=C2)=S)C=CC=C1OC
Molecular Formula
C13H16N4O2S
Molecular Weight
292.36
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100764R/
Scientific Category
Reference Standards
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