Toxoflavin (Standard)
Toxoflavin (Standard) is the analytical standard of Toxoflavin. This product is intended for research and analytical applications. Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4) /β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor and antibiotic activity[1][2].
Product Specifications
Product Name Alternative
Xanthothricin (Standard) ; Toxoflavine (Standard) ; PKF-118-310 (Standard)
UNSPSC
12352005
Target
Antibiotic; Bacterial; Histone Demethylase; Reference Standards; β-catenin
Related Pathways
Anti-infection; Epigenetics; Others; Stem Cell/Wnt
Field of Research
Cancer; Infection
Smiles
O=C(C1=NC=NN(C)C1=N2)N(C)C2=O
Molecular Formula
C7H7N5O2
Molecular Weight
193.16
References & Citations
[1]Wei W, et al. Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo. Int J Cancer. 2010 May 15;126 (10) :2426-36.|[2]Franci G, et al. Identification and characterization of PKF118-310 as a KDM4A inhibitor. Epigenetics. 2017 Mar 4;12 (3) :198-205.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100760R/
Scientific Category
Reference Standards
CAS Number
[84-82-2]
Available Sizes
Curated Selection
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