Toxoflavin (Standard)

Toxoflavin (Standard) is the analytical standard of Toxoflavin. This product is intended for research and analytical applications. Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4) /β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor and antibiotic activity[1][2].

Product Specifications

CAS Number

[84-82-2]

Product Name Alternative

Xanthothricin (Standard) ; Toxoflavine (Standard) ; PKF-118-310 (Standard)

UNSPSC

12352005

Target

Antibiotic; Bacterial; Histone Demethylase; Reference Standards; β-catenin

Related Pathways

Anti-infection; Epigenetics; Others; Stem Cell/Wnt

Field of Research

Cancer; Infection

Smiles

O=C(C1=NC=NN(C)C1=N2)N(C)C2=O

Molecular Formula

C7H7N5O2

Molecular Weight

193.16

References & Citations

[1]Wei W, et al. Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo. Int J Cancer. 2010 May 15;126 (10) :2426-36.|[2]Franci G, et al. Identification and characterization of PKF118-310 as a KDM4A inhibitor. Epigenetics. 2017 Mar 4;12 (3) :198-205.