STAT3-IN-1 (Standard)
STAT3-IN-1 (Standard) is the analytical standard of STAT3-IN-1. This product is intended for research and analytical applications. STAT3-IN-1 (compound 7d) is an excellent, selective and orally active STAT3 inhibitor, with IC50 values of 1.82 μM and 2.14 μM in HT29 and MDA-MB 231 cells, respectively. STAT3-IN-1 (compound 7d) induces tumor cells apoptosis[1].
Product Specifications
CAS Number
2059952-75-7
Target
Apoptosis; Reference Standards; STAT
Related Pathways
Apoptosis; JAK/STAT Signaling; Others; Stem Cell/Wnt
Field of Research
Cancer
Smiles
COC1=CC(OC)=CC(/C=C/C2=CC=C(NC(/C=C/C3=CC(OC)=C(OC)C(OC)=C3)=O)C=C2)=C1
Molecular Formula
C28H29NO6
Molecular Weight
475.53
References & Citations
[1]Li S, et al. Discovery of oral-available resveratrol-caffeic acid based hybrids inhibiting acetylated and phosphorylated STAT3 protein. Eur J Med Chem. 2016 Nov 29;124:1006-1018.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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