HeE1-2Tyr (Standard)
HeE1-2Tyr (Standard) is the analytical standard of HeE1-2Tyr. This product is intended for research and analytical applications. HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. HeE1-2Tyr significantly inhibits West Nile, Dengue and SARS-CoV-2 RdRps (IC50 of 27.6 μM) activity in vitro[1][2].
Product Specifications
CAS Number
2245195-67-7
Target
Dengue Virus; Flavivirus; Reference Standards; SARS-CoV
Related Pathways
Anti-infection; Others
Field of Research
Infection
Smiles
OC(C=C1)=CC=C1C[C@@H](C(O)=O)NC(C(C=C2C3=CC=CC=C3)=C4SC5=CC=C(OC6CCCCC6)C=C5N4C2=O)=O
Molecular Formula
C33H30N2O6S
Molecular Weight
582.67
References & Citations
[1]Delia Tarantino, et al. Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor. Antiviral Res. 2016 Oct;134:226-235.|[2]Milan Dejmek, et al. Non-Nucleotide RNA-Dependent RNA Polymerase Inhibitor That Blocks SARS-CoV-2 Replication. Viruses. 2021 Aug 11;13 (8) :1585.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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