PSB-12379 (Standard)
PSB-12379 (Standard) is the analytical standard of PSB-12379. This product is intended for research and analytical applications. PSB-12379, a nucleotide analogue, is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human)[2].
Product Specifications
CAS Number
1802226-78-3
Target
CD73; Reference Standards
Related Pathways
Immunology/Inflammation; Others
Field of Research
Cancer
Smiles
O=P(O)(O)CP(OC[C@H]1O[C@@H](N2C=NC3=C(NCC4=CC=CC=C4)N=CN=C32)[C@H](O)[C@@H]1O)(O)=O
Molecular Formula
C18H23N5O9P2
Molecular Weight
515.35
References & Citations
[1]Bhattarai S, et al. α, β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5'-Nucleotidase (CD73) Inhibitors. J Med Chem. 2015 Aug 13;58 (15) :6248-63.|[2]X-Ray Co-Crystal Structure Guides the Way to Subnanomolar Competitive Ecto-5 -Nucleotidase (CD73) Inhibitors for Cancer Immunotherapy Sanjay Bhattarai. Adv. Therap. 2019, 2, 1900075.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
#31027 1 Kit
AccuClear® Ultra High Sensitivity dsDNA Quantitation Solution (1000 assays)
Sign In for Pricing
View Details 
![Myozenin 1 (MYOZ1) Mouse Monoclonal Antibody [Clone ID: OTI4C2]](https://cdn.genprice.uk/products/937/68dd18ba061270361e90845a/imageurl/cf808910.webp)
CF808910 100 µg
Myozenin 1 (MYOZ1) Mouse Monoclonal Antibody [Clone ID: OTI4C2]
Sign In for Pricing
View Details 
![SFPQ Rabbit Monoclonal Antibody [Clone ID: 24GB1220]](https://cdn.genprice.uk/products/937/6868c301994c49e6dc3ed143/imageurl/ta425216.webp)
TA425216 100 µL
SFPQ Rabbit Monoclonal Antibody [Clone ID: 24GB1220]
Sign In for Pricing
View Details