(S) -GNE-140 (Standard)

(S) -GNE-140 (Standard) is the analytical standard of (S) -GNE-140 (HY-100742B) . This product is intended for research and analytical applications. (S) -GNE-140 is the less active enantiomer of GNE-140 which can inhibit Lactate dehydrogenase A (LDHA) .

Product Specifications

CAS Number

[2003234-64-6]

Target

Lactate Dehydrogenase; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

O=C1N[C@](C2=CSC=C2)(C3=CC=C(N4CCOCC4)C=C3)CC(O)=C1SC5=CC=CC=C5Cl

Molecular Formula

C25H23ClN2O3S2

Molecular Weight

499.04

References & Citations

[1]Purkey HE, et al. Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice. ACS Med Chem Lett. 2016 Aug 26;7 (10) :896-901.