RA190 (Standard)
RA190 (Standard) is the analytical standard of RA190 (HY-100739) . This product is intended for research and analytical applications. RA190, a bis-benzylidine piperidon, inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.
Product Specifications
CAS Number
[1617495-03-0]
Target
Proteasome; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
O=C1/C(CN(C([C@@H](N)CC2=CC=CC=C2)=O)C/C1=C/C3=CC=C(Cl)C(Cl)=C3)=C\C4=CC=C(Cl)C(Cl)=C4.[H]Cl
Molecular Formula
C28H23Cl5N2O2
Molecular Weight
596.76
References & Citations
[1]Anchoori RK, et al. A bis-benzylidine piperidone targeting proteasome ubiquitin receptor RPN13/ADRM1 as a therapy for cancer. Cancer Cell. 2013 Dec 9;24 (6) :791-805.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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