C 87 (Standard)
C 87 (Standard) is the analytical standard of C 87. This product is intended for research and analytical applications. C 87 is a novel small-molecule TNFα inhibitor; potently inhibits TNFα-induced cytotoxicity with an IC50 of 8.73 μM.
Product Specifications
CAS Number
332420-90-3
Target
Reference Standards; TNF Receptor
Related Pathways
Apoptosis; Others
Field of Research
Inflammation/Immunology
Smiles
O=C(N(C1=NC(C2=CC=CC=C2)=CS1)N=C/3C4=CC=CC=C4)C3=N\NC5=CC=C(Cl)C([N+]([O-])=O)=C5
Molecular Formula
C24H15ClN6O3S
Molecular Weight
502.93
References & Citations
[1]Ma L, et al. A novel small-molecule tumor necrosis factor α inhibitor attenuates inflammation in a hepatitis mouse model. J Biol Chem. 2014 May 2;289 (18) :12457-66.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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