Cambinol (Standard)
Cambinol (Standard) is the analytical standard of Cambinol. This product is intended for research and analytical applications. Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 μM and 59 μM, respectively. Cambinol is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) [1][2].
Product Specifications
CAS Number
14513-15-6
UNSPSC
12352005
Target
Apoptosis; Phospholipase; Reference Standards; Sirtuin
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
O=C(C(CC1=C2C=CC=CC2=CC=C1O)=C(C3=CC=CC=C3)N4)NC4=S
Molecular Formula
C21H16N2O2S
Molecular Weight
360.43
References & Citations
[1]Heltweg B, et al. Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes. Cancer Res. 2006 Apr 15;66 (8) :4368-77.|[2]Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35 (1) :1322-1330.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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