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BMT-145027 (Standard)

BMT-145027 (Standard) is the analytical standard of BMT-145027. This product is intended for research and analytical applications. BMT-145027 is an mGluR5 positive allosteric modulator without inherent agonist activity, exhibits an EC50 of 47 nM.

Product Specifications

CAS Number

2018282-44-3

Target

MGluR; Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

ClC(C(C(F)(F)F)=C1)=CC=C1C2=NNC3=NC(C4=CC=CC=C4)=C(C#N)C(C5CC5)=C32

Molecular Formula

C23H14ClF3N4

Molecular Weight

438.83

References & Citations

[1]Hill MD, et al. Development of 1H-Pyrazolo[3,4-b]pyridines as Metabotropic Glutamate Receptor 5 Positive Allosteric Modulators. ACS Med Chem Lett. 2016 Oct 3;7 (12) :1082-1086.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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