BMT-145027 (Standard)
BMT-145027 (Standard) is the analytical standard of BMT-145027 (HY-100728) . This product is intended for research and analytical applications. BMT-145027 is an mGluR5 positive allosteric modulator without inherent agonist activity, exhibits an EC50 of 47 nM.
Product Specifications
CAS Number
[2018282-44-3]
Target
MGluR; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
ClC(C(C(F)(F)F)=C1)=CC=C1C2=NNC3=NC(C4=CC=CC=C4)=C(C#N)C(C5CC5)=C32
Molecular Formula
C23H14ClF3N4
Molecular Weight
438.83
References & Citations
[1]Hill MD, et al. Development of 1H-Pyrazolo[3,4-b]pyridines as Metabotropic Glutamate Receptor 5 Positive Allosteric Modulators. ACS Med Chem Lett. 2016 Oct 3;7 (12) :1082-1086.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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