AM-2099 (Standard)
AM-2099 (Standard) is the analytical standard of AM-2099 (HY-100727) . This product is intended for research and analytical applications. AM-2099 is a potent and selective inhibitor of voltage-gated sodium channel Nav1.7 with an IC50 of 0.16 μM for human Nav1.7.
Product Specifications
CAS Number
[1443373-17-8]
Target
Reference Standards; Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Neurological Disease
Smiles
COC1=CC(C(F)(F)F)=CC=C1C2=NC=NC3=CC(S(=O)(NC4=NC=CS4)=O)=CC=C32
Molecular Formula
C19H13F3N4O3S2
Molecular Weight
466.46
References & Citations
[1]Marx IE, et al. Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable in Vivo Target Engagement. ACS Med Chem Lett. 2016 Sep 21;7 (12) :1062-1067.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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