TPOP146 (Standard)
TPOP146 (Standard) is the analytical standard of TPOP146. This product is intended for research and analytical applications. TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor with Kd values of 134 nM and 5.02 μM for CBP and BRD4.
Product Specifications
CAS Number
2018300-62-2
Target
Epigenetic Reader Domain; Histone Acetyltransferase; Reference Standards
Related Pathways
Epigenetics; Others
Field of Research
Cancer
Smiles
COC1=CC(OC)=CC(C2=CC(C(N[C@H]3CCCN(C)C3)=O)=C(OCCN(C(CC)=O)C4)C4=C2)=C1
Molecular Formula
C27H35N3O5
Molecular Weight
481.58
References & Citations
[1]Popp TA, et al. Development of Selective CBP/P300 Benzoxazepine Bromodomain Inhibitors. J Med Chem. 2016 Oct 13;59 (19) :8889-8912.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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