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TPOP146 (Standard)

TPOP146 (Standard) is the analytical standard of TPOP146 (HY-100697) . This product is intended for research and analytical applications. TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor with Kd values of 134 nM and 5.02 μM for CBP and BRD4.

Product Specifications

CAS Number

[2018300-62-2]

Target

Epigenetic Reader Domain; Histone Acetyltransferase; Reference Standards

Related Pathways

Epigenetics; Others

Field of Research

Cancer

Smiles

COC1=CC(OC)=CC(C2=CC(C(N[C@H]3CCCN(C)C3)=O)=C(OCCN(C(CC)=O)C4)C4=C2)=C1

Molecular Formula

C27H35N3O5

Molecular Weight

481.58

References & Citations

[1]Popp TA, et al. Development of Selective CBP/P300 Benzoxazepine Bromodomain Inhibitors. J Med Chem. 2016 Oct 13;59 (19) :8889-8912.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Curated Selection

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