Lin28-let-7a antagonist 1 (Standard)

Lin28-let-7a antagonist 1 (Standard) is the analytical standard of Lin28-let-7a antagonist 1 (HY-100692) . This product is intended for research and analytical applications. Lin28-let-7a antagonist 1 shows a clear antagonistic effect against the Lin28-let-7a interaction with an IC50 of 4.03 μM for Lin28A-let-7a-1 interaction.

Product Specifications

CAS Number

[2024548-03-4]

Target

MicroRNA; Reference Standards

Related Pathways

Epigenetics; Others

Field of Research

Cancer

Smiles

O=C(O)C(C=C1)=CC=C1N2N=CC3=C2C4=CC([N+]([O-])=O)=C(N5CCN(C(OCC6=CC=CC=C6)=O)CC5)C=C4OC3(C)C

Molecular Formula

C31H29N5O7

Molecular Weight

583.59

References & Citations

[1]Lim D, et al. Discovery of a Small-Molecule Inhibitor of Protein-MicroRNA Interaction Using Binding Assay with a Site-Specifically Labeled Lin28. J Am Chem Soc. 2016 Oct 7.