GSK2837808A (Standard)

GSK2837808A (Standard) is the analytical standard of GSK2837808A (HY-100681) . This product is intended for research and analytical applications. GSK2837808A is a potent and selective lactate dehydrogenase A (LDHA) inhibitor with IC50s of 2.6 and 43 nM for hLDHA and hLDHB, respectively.

Product Specifications

CAS Number

[1445879-21-9]

Target

Lactate Dehydrogenase; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

O=C(O)C1=CC(OC2=CC(F)=CC(F)=C2)=CC(NC3=C(S(=O)(NC4CC4)=O)C=NC5=CC(C6=CN=C(OC)N=C6OC)=CC=C35)=C1

Molecular Formula

C31H25F2N5O7S

Molecular Weight

649.62

References & Citations

[1]Billiard J, et al. Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells. Cancer Metab. 2013 Sep 6;1 (1) :19.