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JTE-013 (Standard)

JTE-013 (Standard) is the analytical standard of JTE-013. This product is intended for research and analytical applications. JTE-013 is a potent and specific S1P2 (Sphingosine-1-Phosphate 2; EDG-5) antagonist. JTE-013 inhibits the specific binding of radiolabeled S1P to human and rat S1P2 with IC50s of 17 nM and 22 nM, respectively[1].

Product Specifications

CAS Number

383150-41-2

UNSPSC

12352005

Target

Apoptosis; LPL Receptor; Reference Standards

Related Pathways

Apoptosis; GPCR/G Protein; Others

Field of Research

Cancer

Smiles

CC(C1=C2C(N(C)N=C2C)=NC(NNC(NC3=CC(Cl)=NC(Cl)=C3)=O)=C1)C

Molecular Formula

C17H19Cl2N7O

Molecular Weight

408.29

References & Citations

[1]Li MH, et al. Antitumor Activity of a Novel Sphingosine-1-Phosphate 2 Antagonist, AB1, in Neuroblastoma. J Pharmacol Exp Ther. 2015 Sep;354 (3) :261-8.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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