JYL 1421 (Standard)

JYL 1421 (Standard) is the analytical standard of JYL 1421 (HY-100668) . This product is intended for research and analytical applications. JYL 1421 is a TRPV1 receptor antagonist, with an IC50 of 8 nM.

Product Specifications

CAS Number

[401907-26-4]

Target

Reference Standards; TRP Channel

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

CS(=O)(NC1=CC=C(CNC(NCC2=CC=C(C(C)(C)C)C=C2)=S)C=C1F)=O

Molecular Formula

C20H26FN3O2S2

Molecular Weight

423.57

References & Citations

[1]Jakab B, et al. Pharmacological characterization of the TRPV1 receptor antagonist JYL1421 (SC0030) in vitro and in vivo in the rat. Eur J Pharmacol. 2005 Jul 4;517 (1-2) :35-44.