AZD5153 (6-Hydroxy-2-naphthoic acid) (Standard)
AZD5153 (6-Hydroxy-2-naphthoic acid) (Standard) is the analytical standard of AZD5153 (6-Hydroxy-2-naphthoic acid). This product is intended for research and analytical applications. AZD5153 6-Hydroxy-2-naphthoic acid is the 6-Hydroxy-2-naphthoic acid of AZD5153. AZD5153 is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor; disrupts BRD4 with an IC50 of 1.7 nM.
Product Specifications
CAS Number
1869912-40-2
Target
Epigenetic Reader Domain; Reference Standards
Related Pathways
Epigenetics; Others
Field of Research
Cancer
Smiles
O=C(C1=CC=C2C=C(O)C=CC2=C1)O.O=C3N(C)CCN(CCOC4=CC=C(C5CCN(C6=NN7C(C=C6)=NN=C7OC)CC5)C=C4)[C@@H]3C
Molecular Formula
C36H41N7O6
Molecular Weight
667.75
References & Citations
[1]Rhyasen GW, et al. AZD5153: A Novel Bivalent BET Bromodomain Inhibitor Highly Active against Hematologic Malignancies. Mol Cancer Ther. 2016 Nov;15 (11) :2563-2574.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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