MDL 72527 (Standard)
MDL 72527 (Standard) is the analytical standard of MDL 72527. This product is intended for research and analytical applications. MDL 72527 is a potent polyamine oxidase (PAO) inhibitor. MDL 72527 shows a lysosomotropic effect. MDL 72527 shows neuroprotective effects[1][2].
Product Specifications
CAS Number
93565-01-6
Target
Monoamine Oxidase; Reference Standards
Related Pathways
Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
C=C=CCNCCCCNCC=C=C.[H]Cl.[H]Cl
Molecular Formula
C12H22Cl2N2
Molecular Weight
265.22
References & Citations
[1]Doğan A, et al. Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle cerebral artery occlusion. J Neurochem. 1999 Feb;72 (2) :765-70.|[2]Agostinelli E, et al. Toxicity of enzymatic oxidation products of spermine to human melanoma cells (M14) : sensitization by heat and MDL 72527. Biochim Biophys Acta. 2006 Oct;1763 (10) :1040-50.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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