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RPR121056 (Standard)

RPR121056 (Standard) is the analytical standard of RPR121056. This product is intended for research and analytical applications. RPR121056 (APC) is a metabolite of Irinotecan (CPT-11), which is generated by CYP3A4. Irinotecan (CPT-11) is an antineoplastic agent that inhibits topoisomerase type I, causing cell death, and is widely used in the treatment of colorectal cancer. Irinotecan also directly inhibits AChE[1].

Product Specifications

CAS Number

181467-56-1

Product Name Alternative

APC (Standard)

UNSPSC

12352005

Target

Cholinesterase (ChE) ; Drug Metabolite; Reference Standards; Topoisomerase

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Field of Research

Cancer

Smiles

O=C(N1CCC(NCCCCC(O)=O)CC1)OC2=CC=C3N=C4C(CN5C(C(COC([C@@]6(CC)O)=O)=C6C=C54)=O)=C(CC)C3=C2

Molecular Formula

C33H38N4O8

Molecular Weight

618.68

References & Citations

[1]Alvau MD, et al. Enzyme-Based Electrochemical Biosensor for Therapeutic Drug Monitoring of Anticancer Drug Irinotecan. Anal Chem. 2018 May 15;90 (10) :6012-6019.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

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