S3I-1757
S3I-1757 is a STAT3 inhibitor. S3I-1757 inhibits the phosphorylation and dimerization of STAT3. S3I-1757 can be used for the research of STAT3 hyperactive cancers such as melanoma[1].
Product Specifications
CAS Number
1456602-51-9
UNSPSC
12352005
Target
STAT
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C(O)C1=CC(N(CC2=CC=C(C3CCCCC3)C=C2)C(C4=CC=C(OC5=CC=CC=C5)C=C4)=O)=CC=C1O
Molecular Formula
C33H31NO5
Molecular Weight
521.60
References & Citations
[1]Soleimani AH, et al. Micellar nano-carriers for the delivery of STAT3 dimerization inhibitors to melanoma. Drug Deliv Transl Res. 2017 Aug;7 (4) :571-581.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
STAT3
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