(R) -JNJ-40418677 (Standard)
(R) -JNJ-40418677 (Standard) is the analytical standard of (R) -JNJ-40418677 (HY-100604A) . This product is intended for research and analytical applications. (R) -JNJ-40418677 is the R-enantiomer of JNJ-40418677 (HY-100604) [1].
Product Specifications
CAS Number
[1146594-85-5]
Target
Amyloid-β; Reference Standards; γ-secretase
Related Pathways
Neuronal Signaling; Others; Stem Cell/Wnt
Field of Research
Others
Smiles
CC(C)C[C@H](C1=CC(C2=CC=C(C=C2)C(F)(F)F)=CC(C3=CC=C(C=C3)C(F)(F)F)=C1)C(O)=O
Molecular Formula
C26H22F6O2
Molecular Weight
480.44
References & Citations
[1]Van Broeck B, et al. Chronic treatment with a novel γ-secretase modulator, JNJ-40418677, inhibits amyloid plaque formation in a mouse model of Alzheimer's disease. Br J Pharmacol. 2011 May;163 (2) :375-89.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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