Urolithin A-13C6

Urolithin A-13C6 is the 13C-labeled Urolithin A (HY-100599) . Urolithin A, a gut-microbial metabolite of ellagic acid, exerts anti-inflammatory, antiproliferative, and antioxidant properties. Urolithin A induces autophagy and apoptosis, suppresses cell cycle progression, and inhibits DNA synthesis[1][2].

Product Specifications

UNSPSC

12352005

Target

Apoptosis; Autophagy; DNA/RNA Synthesis; Drug Metabolite; Endogenous Metabolite; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)

Related Pathways

Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C1[13C]2=[13CH][13C](O)=[13CH][13CH]=[13C]2C3=CC=C(O)C=C3O1

Molecular Formula

C7 13C6H8O4

Molecular Weight

234.16

References & Citations

[1]Gong Z, et al. Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice. |[2]Wang Y, et al. In vitro antiproliferative and antioxidant effects of urolithin A, the colonic metabolite of ellagic acid, on hepatocellular carcinomas HepG2 cells. Toxicol In Vitro. 2015 Aug;29 (5) :1107-15.