Urolithin A (Standard)

Atractylodin (Standard) is the analytical standard of Atractylodin. This product is intended for research and analytical applications. Atractylodin (Atractydin) is an orally active active ingredient obtained from the rhizome of Atractylodes lancea and A. chinensis. Atractylodin is a natural insecticide. Atractylodin has anti-inflammatory activity[1][2][3].

Product Specifications

CAS Number

[1143-70-0]

UNSPSC

12352005

Target

Apoptosis; Autophagy; DNA/RNA Synthesis; Drug Metabolite; Endogenous Metabolite; Reactive Oxygen Species (ROS) ; Reference Standards

Related Pathways

Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Cancer

Smiles

O=C1C2=CC(O)=CC=C2C3=CC=C(O)C=C3O1

Molecular Formula

C13H8O4

Molecular Weight

228.20

References & Citations

[5]Wang Y, et al. In vitro antiproliferative and antioxidant effects of urolithin A, the colonic metabolite of ellagic acid, on hepatocellular carcinomas HepG2 cells. Toxicol In Vitro. 2015 Aug;29 (5) :1107-15.|[6]Ishimoto H, et al. In vivo anti-inflammatory and antioxidant properties of ellagitannin metabolite urolithin A. Bioorg Med Chem Lett. 2011 Oct 1;21 (19) :5901-4.|[1]Gong Z, et al. Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice.|[2]Zhao W, et al. Metabolite of ellagitannins, urolithin A induces autophagy and inhibits metastasis in human sw620colorectal cancer cells. Mol Carcinog. 2018 Feb;57 (2) :193-200.|[3]Qiu Z, et al. In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells. Food Chem Toxicol. 2013 Sep;59:428-37.|[4]González-Sarrías A, et al. Antiproliferative activity of the ellagic acid-derived gut microbiota isourolithin A and comparison with its urolithin A isomer: the role of cell metabolism.Eur J Nutr. 2017 Mar;56 (2) :831-841.