(-) - (S) -Equol (Standard)

(-) - (S) -Equol (Standard) is the analytical standard of (-) - (S) -Equol. This product is intended for research and analytical applications. (-) - (S) -Equol is a high affinity ligand for estrogen receptor β with a Ki of 0.73 nM.

Product Specifications

CAS Number

[531-95-3]

UNSPSC

12352005

Target

Endogenous Metabolite; Estrogen Receptor/ERR; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer; Metabolic Disease; Neurological Disease

Purity

98.90

Smiles

OC1=CC=C2C[C@H](COC2=C1)C3=CC=C(C=C3)O

Molecular Formula

C15H14O3

Molecular Weight

242.27

References & Citations

[1]Setchell KD, et al. S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora. Am J Clin Nutr. 2005 May;81 (5) :1072-9.|[2]Lu Z, et al. S-equol, a Secondary Metabolite of Natural Anticancer Isoflavone Daidzein, Inhibits Prostate Cancer Growth In Vitro and In Vivo, Though Activating the Akt/FOXO3a Pathway. Curr Cancer Drug Targets. 2016;16 (5) :455-65.|[3]Horiuchi H, et al. S-equol nantioselectively activates cAMP-protein kinase A signaling and reduces alloxan-induced cell death in INS-1 pancreatic β-cells. J Nutr Sci Vitaminol (Tokyo) . 2014;60 (4) :291-6.