Maropitant (Standard)
Maropitant (Standard) is the analytical standard of Maropitant. This product is intended for research and analytical applications. Maropitant is a selective and orally active neurokinin (NK1) receptor antagonist. Maropitant acts by blocking the binding of substance P within the emetic center and the chemoreceptor trigger zone (CRTZ) . Maropitant is highly effective in preventing vomiting[1][2].
Product Specifications
CAS Number
147116-67-4
UNSPSC
12352005
Target
Neurokinin Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease; Endocrinology
Smiles
CC(C)(C)C1=CC=C(OC)C(CN[C@@H]2[C@H](C(C3=CC=CC=C3)C4=CC=CC=C4)N5CCC2CC5)=C1
Molecular Formula
C32H40N2O
Molecular Weight
468.67
References & Citations
[1]Hay Kraus BL. Efficacy of orally administered maropitant citrate in preventing vomiting associated with hydromorphone administration in dogs. J Am Vet Med Assoc. 2014 May 15;244 (10) :1164-9.|[2]Williams-Fritze MJ, et al. Maropitant citrate for treatment of ulcerative dermatitis in mice with a C57BL/6 background. J Am Assoc Lab Anim Sci. 2011 Mar;50 (2) :221-6.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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