Maropitant (citrate hydrate)

Maropitant citrate hydrate is the citrate hydrate of Maropitant (HY-10053) . Maropitant is an orally active NK1 receptor antagonist. Maropitant prevents vomiting and inhibits ulcerative dermatitis[1][2].

Product Specifications

CAS Number

[359875-09-5]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Neurokinin Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

OC(C(O)=O)(CC(O)=O)CC(O)=O.CC(C)(C)C1=CC=C(OC)C(CN[C@@H]2[C@H](C(C3=CC=CC=C3)C4=CC=CC=C4)N5CCC2CC5)=C1.O

Molecular Formula

C38H50N2O9

Molecular Weight

678.81

Precautions

P261-P280-P302+P352

References & Citations

[1]Hay Kraus BL. Efficacy of orally administered maropitant citrate in preventing vomiting associated with hydromorphone administration in dogs. J Am Vet Med Assoc. 2014 May 15;244 (10) :1164-9. |[2]Williams-Fritze MJ, et al. Maropitant citrate for treatment of ulcerative dermatitis in mice with a C57BL/6 background. J Am Assoc Lab Anim Sci. 2011 Mar;50 (2) :221-6.