CD437 (Standard)

CD437 (Standard) is the analytical standard of CD437. This product is intended for research and analytical applications. CD437 is a selective Retinoic Acid Receptor γ (RARγ) agonist.

Product Specifications

CAS Number

[125316-60-1]

Product Name Alternative

AHPN (Standard)

UNSPSC

12352005

Target

Autophagy; RAR/RXR; Reference Standards

Related Pathways

Autophagy; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Smiles

O=C(C1=CC=C2C=C(C3=CC=C(O)C(C4(C5)CC6CC5CC(C6)C4)=C3)C=CC2=C1)O

Molecular Formula

C27H26O3

Molecular Weight

398.49

References & Citations

[1]Li Y, et al. Molecular determinants of AHPN (CD437) -induced growth arrest and apoptosis in human lung cancer cell lines. Mol Cell Biol. 1998 Aug;18 (8) :4719-31.|[2]Schadendorf D, et al. Treatment of melanoma cells with the synthetic retinoid CD437 induces apoptosis via activation of AP-1 in vitro, and causes growth inhibition in xenografts in vivo. J Cell Biol. 1996 Dec;135 (6 Pt 2) :1889-98.