CD437 (Standard)
CD437 (Standard) is the analytical standard of CD437. This product is intended for research and analytical applications. CD437 is a selective Retinoic Acid Receptor γ (RARγ) agonist.
Product Specifications
CAS Number
[125316-60-1]
Product Name Alternative
AHPN (Standard)
UNSPSC
12352005
Target
Autophagy; RAR/RXR; Reference Standards
Related Pathways
Autophagy; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
O=C(C1=CC=C2C=C(C3=CC=C(O)C(C4(C5)CC6CC5CC(C6)C4)=C3)C=CC2=C1)O
Molecular Formula
C27H26O3
Molecular Weight
398.49
References & Citations
[1]Li Y, et al. Molecular determinants of AHPN (CD437) -induced growth arrest and apoptosis in human lung cancer cell lines. Mol Cell Biol. 1998 Aug;18 (8) :4719-31.|[2]Schadendorf D, et al. Treatment of melanoma cells with the synthetic retinoid CD437 induces apoptosis via activation of AP-1 in vitro, and causes growth inhibition in xenografts in vivo. J Cell Biol. 1996 Dec;135 (6 Pt 2) :1889-98.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Curated Selection
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