PD150606 (Standard)

PD150606 (Standard) is the analytical standard of PD150606 (HY-100529) . This product is intended for research and analytical applications. PD 150606 is a selective, cell-permeable non-peptide calpain inhibitor with Ki values of 0.21 μM and 0.37 μM for μ- and m-calpains respectively, which is neuroprotective[1].

Product Specifications

CAS Number

[179528-45-1]

Target

Proteasome; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

O=C(O)/C(S)=C/C1=CC=C(I)C=C1

Molecular Formula

C9H7IO2S

Molecular Weight

306.12

References & Citations

[1]1. Wang KK et al. An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective. Proc Natl Acad Sci U S A. 1996 Jun 25;93 (13) :6687-92.|[2]2. Squier MK , et al. Calpain and calpastatin regulate neutrophil apoptosis. J Cell Physiol. 1999 Mar;178 (3) :311-9.