NVS-PAK1-1 (Standard)
NVS-PAK1-1 (Standard) is the analytical standard of NVS-PAK1-1. This product is intended for research and analytical applications. NVS-PAK1-1, a chemical probe, is a potent and selective allosteric PAK1 inhibitor with an IC50 of 5 nM[1].
Product Specifications
CAS Number
1783816-74-9
Target
PAK; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Others
Field of Research
Cancer
Smiles
FC1=CC2=C(C=C1)N(CC(F)F)C3=C(C=C(Cl)C=C3)C(N[C@H]4CCN(C(NC(C)C)=O)C4)=N2
Molecular Formula
C23H25ClF3N5O
Molecular Weight
479.93
References & Citations
[1]Karpov AS, et al. Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor. ACS Med Chem Lett. 2015 May 22;6 (7) :776-81.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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