T-26c (Standard)
T-26c (Standard) is the analytical standard of T-26c (HY-100518) . This product is intended for research and analytical applications. T-26c, a chemical probe, is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes[1].
Product Specifications
CAS Number
[869296-13-9]
Target
MMP; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology
Smiles
COC1=CC=CC(CNC(C2=NC(SC=C3COCC4=CC=C(C(O)=O)C=C4)=C3C(N2)=O)=O)=C1
Molecular Formula
C24H21N3O6S
Molecular Weight
479.51
References & Citations
[1]Nara H, et al. Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1″ binding site. Bioorg Med Chem. 2014 Oct 1;22 (19) :5487-505.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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