GSK484 (hydrochloride) (Standard)
GSK484 (hydrochloride) (Standard) is the analytical standard of GSK484 (hydrochloride). This product is intended for research and analytical applications. GSK484 hydrochloride is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. GSK484 hydrochloride demonstrates high affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium. In the presence of 2 mM Calcium, notably lower potency (250 nM) is observed.
Product Specifications
CAS Number
1652591-81-5
Target
Protein Arginine Deiminase; Reference Standards
Related Pathways
Epigenetics; Others
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Smiles
O=C(N1C[C@H](N)[C@H](O)CC1)C2=CC(OC)=C3C(N=C(C(N4CC5CC5)=CC6=C4C=CC=C6)N3C)=C2.[H]Cl
Molecular Formula
C27H32ClN5O3
Molecular Weight
510.03
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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