ITSA-1 (Standard)
ITSA-1 (Standard) is the analytical standard of ITSA-1 (HY-100508) . This product is intended for research and analytical applications. ITSA-1 is an activator of histone deacetylase (HDAC), and counteract trichostatin A (TSA) -induced cell cycle arrest, histone acetylation, and transcriptional activation[1].
Product Specifications
CAS Number
[200626-61-5]
Target
HDAC; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Others
Field of Research
Cancer
Smiles
O=C(N1N=NC2=CC=CC=C21)C3=CC=C(Cl)C=C3Cl
Molecular Formula
C13H7Cl2N3O
Molecular Weight
292.12
References & Citations
[1]Koeller KM et al. Chemical genetic modifier screens: small molecule trichostatin suppressors as probes of intracellular histoneand tubulin acetylation. Chem Biol. 2003 May;10 (5) :397-410.|[2]Behera J, et al. Hydrogen Sulfide Promotes Bone Homeostasis by Balancing Inflammatory Cytokine Signaling in CBS-Deficient Mice through an Epigenetic Mechanism. Sci Rep. 2018 Oct 15;8 (1) :15226.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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