M2698 (Standard)
M2698 (Standard) is the analytical standard of M2698 (HY-100501) . This product is intended for research and analytical applications. M2698 (MSC2363318A) is an orally active, ATP competitive, selective p70S6K and Akt dual-inhibitor with IC50s of 1 nM for p70S6K, Akt1 and Akt3. M2698 can cross the blood-brain barrier and has anti-cancer activity[1].
Product Specifications
CAS Number
[1379545-95-5]
Target
Akt; Reference Standards; Ribosomal S6 Kinase (RSK)
Related Pathways
MAPK/ERK Pathway; Others; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=C(C1=CC=CC2=C(N[C@@H](C3=CC=C(Cl)C(C(F)(F)F)=C3)CN4CCC4)N=CN=C12)N
Molecular Formula
C21H19ClF3N5O
Molecular Weight
449.86
References & Citations
[1]Machl A, et al. M2698 is a potent dual-inhibitor of p70S6K and Akt that affects tumor growth in mouse models of cancer and crosses the blood-brain barrier. Am J Cancer Res. 2016 Mar 15;6 (4) :806-18.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
