GSK2256098 (Standard)
GSK2256098 (Standard) is the analytical standard of GSK2256098. This product is intended for research and analytical applications. GSK2256098 is a selective FAK kinase inhibitor, which inhibits growth and survival of pancreatic ductal adenocarcinoma cells.
Product Specifications
CAS Number
1224887-10-8
Target
Apoptosis; FAK; Reference Standards
Related Pathways
Apoptosis; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(NOC)C1=CC=CC=C1NC2=CC(NC3=CC(C)=NN3C(C)C)=NC=C2Cl
Molecular Formula
C20H23ClN6O2
Molecular Weight
414.89
References & Citations
[1]Zhang J, et al. A small molecule FAK kinase inhibitor, GSK2256098, inhibits growth and survival of pancreatic ductal adenocarcinoma cells. Cell Cycle. 2014;13 (19) :3143-9.|[2]Thanapprapasr D, et al. PTEN Expression as a Predictor of Response to Focal Adhesion Kinase Inhibition in Uterine Cancer. Mol Cancer Ther. 2015 Jun;14 (6) :1466-75.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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