GSK2256098 (Standard)

GSK2256098 (Standard) is the analytical standard of GSK2256098 (HY-100498) . This product is intended for research and analytical applications. GSK2256098 is a selective FAK kinase inhibitor, which inhibits growth and survival of pancreatic ductal adenocarcinoma cells.

Product Specifications

CAS Number

[1224887-10-8]

Target

Apoptosis; FAK; Reference Standards

Related Pathways

Apoptosis; Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O=C(NOC)C1=CC=CC=C1NC2=CC(NC3=CC(C)=NN3C(C)C)=NC=C2Cl

Molecular Formula

C20H23ClN6O2

Molecular Weight

414.89

References & Citations

[1]Zhang J, et al. A small molecule FAK kinase inhibitor, GSK2256098, inhibits growth and survival of pancreatic ductal adenocarcinoma cells. Cell Cycle. 2014;13 (19) :3143-9.|[2]Thanapprapasr D, et al. PTEN Expression as a Predictor of Response to Focal Adhesion Kinase Inhibition in Uterine Cancer. Mol Cancer Ther. 2015 Jun;14 (6) :1466-75.