BP-1-102 (Standard)
BP-1-102 (Standard) is the analytical standard of BP-1-102. This product is intended for research and analytical applications. BP-1-102 is an orally available, small-molecule inhibitor of transcription factor Stat3, with an IC50 of 6.8 μM.
Product Specifications
CAS Number
1334493-07-0
Target
Reference Standards; STAT
Related Pathways
JAK/STAT Signaling; Others; Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C(O)C1=CC=C(N(CC2=CC=C(C3CCCCC3)C=C2)C(CN(C)S(=O)(C4=C(F)C(F)=C(F)C(F)=C4F)=O)=O)C=C1O
Molecular Formula
C29H27F5N2O6S
Molecular Weight
626.59
References & Citations
[1]Zhang X, et al. Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts. Proc Natl Acad Sci U S A. 2012 Jun 12;109 (24) :9623-8.|[2]De Simone V, et al. Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth. Oncogene. 2015 Jul;34 (27) :3493-503.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC680266-500 1x 500 µL
Human IgG Immunoglobulin (IG266), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470270-500 1x 500 µL
Fibronectin (HFN7.1), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details