H3B-6527 (Standard)
H3B-6527 (Standard) is the analytical standard of H3B-6527. This product is intended for research and analytical applications. H3B-6527 is an orally active, highly selective and covalent FGFR4 inhibitor with an IC50 of.
Product Specifications
CAS Number
1702259-66-2
Target
FGFR; Reference Standards
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C)=C3)=O
Molecular Formula
C29H34Cl2N8O4
Molecular Weight
629.54
References & Citations
[1]Joshi JJ, et al. H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven HepatocellularCarcinoma. Cancer Res. 2017 Dec 15;77 (24) :6999-7013.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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