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H3B-6527 (Standard)

H3B-6527 (Standard) is the analytical standard of H3B-6527. This product is intended for research and analytical applications. H3B-6527 is an orally active, highly selective and covalent FGFR4 inhibitor with an IC50 of.

Product Specifications

CAS Number

1702259-66-2

Target

FGFR; Reference Standards

Related Pathways

Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C)=C3)=O

Molecular Formula

C29H34Cl2N8O4

Molecular Weight

629.54

References & Citations

[1]Joshi JJ, et al. H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven HepatocellularCarcinoma. Cancer Res. 2017 Dec 15;77 (24) :6999-7013.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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