Susalimod
Susalimod is an immunomodulating agent and Sulfasalazine analogue. Susalimod decreases LPS-induced TNF-alpha mouse serum levels[1][2].
Product Specifications
CAS Number
149556-49-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Derivative
Related Pathways
Others
Field of Research
Inflammation/Immunology
Smiles
O=C(O)C1=CC(C#CC2=CC=C(S(=O)(NC3=NC=CC=C3C)=O)C=C2)=CC=C1O
Molecular Formula
C21H16N2O5S
Molecular Weight
408.43
Precautions
P261-P280-P302+P352
References & Citations
[1]Gozzi P, et al. Pharmacokinetic-pharmacodynamic modeling of the immunomodulating agent susalimod and experimentally induced tumor necrosis factor-alpha levels in the mouse. J Pharmacol Exp Ther. 1999 Oct;291 (1) :199-203. |[2]Påhlman , et al. Extensive biliary excretion of the sulfasalazine analogue, susalimod, but different concentrations in the bile duct in various animal species correlating to species-specific hepatobiliary toxicity. Pharmacol Toxicol. 1999 Sep;85 (3) :123-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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