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KC-764

KC-764 is an orally active, reversible cyclooxygenase inhibitor with relative selectivity for platelet cyclooxygenase. KC-764 inhibits platelet thromboxane A2 (TXA2) production and platelet aggregation, with IC50s of 0.23 μM and 26 nM, respectively. KC-764 can be used for the research on antiplatelet and recurrence prevention in ischemic stroke[1].

Product Specifications

CAS Number

94457-09-7

UNSPSC

12352005

Target

Prostaglandin Receptor

Related Pathways

GPCR/G Protein

Field of Research

Neurological Disease

Smiles

O=C(C1=C2C=CC=CN2N=C1C)C3=CNCCC3

Molecular Formula

C14H15N3O

Molecular Weight

241.29

References & Citations

[1]Satoh K, et al. Pyrazolopyridine derivative acts as a novel cyclooxygenase inhibitor: antiplatelet effect in aged patients with ischemic stroke. J Am Geriatr Soc. 1994 Jun;42 (6) :639-42.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 3

Isoform

TXA2/TP

Frequently Asked Questions

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