ZYZ-488 (Standard)

ZYZ-488 (Standard) is the analytical standard of ZYZ-488 (HY-100472) . This product is intended for research and analytical applications. ZYZ-488 is a competitive apoptotic protease activating factor-1 (Apaf-1) inhibitor. ZYZ-488 inhibits the activation of binding protein procaspase-9 and procaspase-3[1].

Product Specifications

CAS Number

[1470302-79-4]

Target

Caspase; Reference Standards

Related Pathways

Apoptosis; Others

Field of Research

Cancer

Smiles

O=C(OCCCCNC(N)=N)C(C=C1OC)=CC(OC)=C1O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O2

Molecular Formula

C20H29N3O11

Molecular Weight

487.46

References & Citations

[1]Wang Y, et al. The discovery of a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1) for ischemic heart: synthesis, activity and target identification. Sci Rep. 2016 Jul 22;6:29820.