NSC781406 (Standard)
NSC781406 (Standard) is the analytical standard of NSC781406. This product is intended for research and analytical applications. NSC781406 is a highly potent PI3K and mTOR inhibitor with an IC50 of 2 nM for PI3Kα.
Product Specifications
CAS Number
1676893-24-5
Target
MTOR; PI3K; Reference Standards
Related Pathways
Others; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
FC1=CC(F)=CC=C1S(=O)(NC2=CC(C3=CC=C(N=CC=C4C#CCN5CCN(S(C)(=O)=O)CC5)C4=C3)=CN=C2OC)=O
Molecular Formula
C29H27F2N5O5S2
Molecular Weight
627.68
References & Citations
[1]Chen Y, et al. Discovery of benzenesulfonamide derivatives as potent PI3K/mTOR dual inhibitors with in vivo efficacies against hepatocellular carcinoma. Bioorg Med Chem. 2016 Mar 1;24 (5) :957-66.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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