CCF642 (Standard)
CCF642 (Standard) is the analytical standard of CCF642 (HY-100430) . This product is intended for research and analytical applications. CCF642 is a potent protein disulfide isomerases (PDI) inhibitor with an IC50 of 2.9 μM. CCF642 causes acute endoplasmic reticulum (ER) stress in multiple myeloma cells accompanied by apoptosis-inducing calcium release. CCF642 has broad anti-multiple myeloma activity[1].
Product Specifications
CAS Number
[346640-08-2]
Target
Apoptosis; PDI; Reference Standards
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
O=C1N(C2=CC=C(OC)C=C2)C(S/C1=C/C3=CC=C([N+]([O-])=O)S3)=S
Molecular Formula
C15H10N2O4S3
Molecular Weight
378.45
References & Citations
[1]Vatolin S et al. Novel Protein Disulfide Isomerase Inhibitor with Anticancer Activity in Multiple Myeloma.
 Cancer Res. 2016 Jun 1;76 (11) :3340-50.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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