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CCF642 (Standard)

CCF642 (Standard) is the analytical standard of CCF642 (HY-100430) . This product is intended for research and analytical applications. CCF642 is a potent protein disulfide isomerases (PDI) inhibitor with an IC50 of 2.9 μM. CCF642 causes acute endoplasmic reticulum (ER) stress in multiple myeloma cells accompanied by apoptosis-inducing calcium release. CCF642 has broad anti-multiple myeloma activity[1].

Product Specifications

CAS Number

[346640-08-2]

Target

Apoptosis; PDI; Reference Standards

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

O=C1N(C2=CC=C(OC)C=C2)C(S/C1=C/C3=CC=C([N+]([O-])=O)S3)=S

Molecular Formula

C15H10N2O4S3

Molecular Weight

378.45

References & Citations

[1]Vatolin S et al. Novel Protein Disulfide Isomerase Inhibitor with Anticancer Activity in Multiple Myeloma.
 Cancer Res. 2016 Jun 1;76 (11) :3340-50.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-100430R/

Scientific Category

Reference Standards

Curated Selection

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